Endocrine Abstracts

Background: Diabetes mellitus (DM) is a common metabolic disorder and is associated with development of chronic macrovascular complications leading to significant morbidity and mortality. The aim of the study was to evaluate the prevalence and clinical profile of macrovascular complications in diabetic patients in Korca, Albania.Material and methods: A total of 456 cases with type 2 DM attending Department of Endocrine (outpatient/inpatient), from Januar...

Background: Fahr’s Syndrome, also known as striopallidodentate calcinosis is a rare form of neurological disorder characterized by abnormal calcified deposits in basal ganglia, cerebellar and cerebral cortex. Its prevalence goes from 2 to 12.5%. Etiology of this disorder is very wide and involves endocrinopathy, mitochondrial myopathies dermatological abnormalities, infectious disease or may be idiopathic. We present a case of a patient with diffuse brain calcifications d...

Introduction: Occult papillary carcinomas are small thyroid carcinomas (<1 cm) diagnosed after an initial manifestation of lymph nodes or distant metastasis. We report two cases of patients with this pattern of clinical presentation.Case description: The first case is a 21-year-old woman, with a one-year history of a growing cervical cyst. Fine needle aspiration of the cyst showed metastasis from papillary thyroid cancer. She had no previous history ...

Introduction: Friedreich ataxia (FA) is a multisystem autosomal recessive disease with progressive clinical course involving the neuromuscular and endocrine system. Individuals with FA have an increased risk of developing diabetes. In FA-associated diabetes, both insulin deficiency and insulin resistance have been reported. We present a case with FA, presented with diabetic ketoacidosis (DKA) as the first presentation of diabetes mellitus.Case Presentati...

Introduction: Thyroid nodule size is routinely assessed and has been a cause for concern, if it is a carcinoma or not.Aim: Our aim was to evaluate the relationship between thyroid nodule size and cancer risk. It was a retrospective analysis of 386 patients with thyroid nodules who referred to surgery in our hospital from January 2011 to March 2016. Patient’s demographic data, nodules size, and final pathology were recorded. All data were analyses us...

Introduction: A thyroid nodule discovered in a patient with Graves’ disease (GD) should be evaluated and managed according to guidelines. A subcentimetre incidental thyroid cancer founded in a patients with GD, without high-risk history, without suspicious sonographic (US) features has not been reported yet.Clinical case: A 40-year-old female patient, presented to our hospital with symptoms of thyrotoxicosis. On physical examination heart rate was 1...

Background: Nephrocalcinosis is characterized by the deposition of calcium products in kidney parenchyma and tubules. It may cause acute or chronic kidney injury or be incidentally detected radiographically in a patient with normal kidney function. Most patients with nephrocalcinosis do not progress to end-stage kidney disease, but with certain underlying conditions, may be associated with progressive kidney dysfunction.Methods: The patient was diagnosed...

Background: Both diabetes mellitus (DM) and tuberculosis (TB) are major public health problems and among the leading causes of morbidity and mortality worldwide. The TB-DM coexistence is known to complicate TB care, control and prevention. Globally, 10.4 million TB cases exists, of them 10 % are linked to DM. People with DM are at four to five times higher risk of getting infected with tuberculosis and evidence show poor TB treatment outcomes. This study purposed to evaluate t...

Introduction: Oral levothyroxine (LT4) is the standard treatment for hypothyroidism and serum TSH represents the best marker for assessing the proper LT4 dose. The absorption and bioequivalence of different commercial LT4 preparations might be variable. The aim of this study is to compare the efficacy of levothyroxine oral solution vs tablets.Methods: Fifty-eight patients (six males, 52 females; average age, 46.9±12....

Background: Diabetes is one of the risk factor for coronary disease. Patient with diabetes have a increased prevalence and incidence of coronary vessels disease compare with the people without diabetes in the general population.Aim and objectives: To compare the study of angiographic coronary results in the patient with and without diabetes.Materials and methods: 172 pacients; 66 with diabetes and 106 without diabetes was admitted ...